GI symptoms typically clear within one to two weeks of the last dose, roughly corresponding to the compound's elimination half-life
It's important to note that while glutathione shows promise, more clinical studies are needed to fully understand its impact on gallbladder health
Shuaibin Zhang, Bing Zhou, Yanyuan Kang, Xia Cui, Ao Liu, Angelique Deleris, Maxim VC Greenberg, Xiekui Cui, Qi Qiu, Falong Lu, James A Wohlschlegel, Steven E Jacobsen and Xiaofeng Cao, "C-terminal domains of histone demethylase JMJ14 interact with a pair of NAC transcription factors to mediate specific chromatin association", Cell Discovery 1 (15003): 1-13 (2015)
In basic terms, NO is produced by an enzyme called nitric oxide synthase (NOS)